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Research at CTEC: Investigators

CTEC comprises a robust group of more than 60 highly productive basic scientists and clinicians who are involved in a broad range of tissue engineering initiatives and programs within the five partnering institutions, in addition to commercial partners and collaborators at many other institutions. For a complete listing of all our investigative staff, please click here.

Principal Investigators

George F. Muschler, M.D. is CTEC's Director. Dr Muschler is the co-Director of the Cleveland Clinic Orthopedic Clinical Research Center and the Vice Chairman of the Department of Biomedical Engineering at the Cleveland Clinic Foundation. Dr. Muschler's career has been devoted to musculoskeletal research, with an emphasis on bone healing and regeneration using tissue engineering methods.

Dr. Muschler leads a number of projects at the Lerner Research Institute and in the Department of Orthopaedic Surgery at the Cleveland Clinic.
To see some of these projects highlighted in a short exerpt from Cleveland Clinic's Medical Miracles series, please click here.


Arnold I. Caplan, Ph.D., is CTEC's Co-Director. Dr. Caplan founded the Skeletal Research Center at Case Western Reserve University and has served as its Director since 1986. Dr. Caplan was also the co-founder of the Midwest Tissue Engineering Consortium (MTEC), which provides students, fellows and junior faculty in the Midwest region an opportunity to present cutting-edge tissue engineering research to their peers. Additionally, his short-course Cell-Based Therapies and Tissue Engineering provides an excellent forum for more than 20 experts in this field each year.


Steven Boyce, Ph.D., is CTEC's Co-Director. Dr. Boyce, based at the University of Cincinnati and Cincinnati Shriner’s Hospital, is an exceptional scientist and an internationally-recognized leader in burn care and wound healing. In 1997, Dr. Steven Boyce founded Cutanogen Corporation, a start-up medical device manufacturing company. He guided
Cutanogen through in-licensing of key technology from the University of California system to help enable his vision for the development and production of Engineered Skin Substitutes.